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With a simple urine test it allows to improve the selection of patients who would benefit from a biopsy, and helps evade it in cases where it is unnecessary.
Based on the mRNA identification of the DLX1 and HOXC6 genes, it is possible to distinguish which patients are at increased risk of clinically significant cancer from those who do not.
Providing a negative predictive value of 99.6% for Gleason Score equal to or greater than 8 and 98% for GS equal to or greater than 7, this means that when this test determines that the risk for an aggressive cancer is low it has a very small margin Of error.
1- MEN WITH HIGH RISK can benefit from biopsy and early detection.
2- MEN WITH VERY LOW RISK can avoid having to undergo unnecessary invasive procedures with routine follow-ups and screenings.
If you have a high prostate-specific antigen (PSA) test result, you may be at risk for prostate cancer.
However, the cause of elevated or increasing PSA may be related to benign (non-cancerous) conditions such as prostatitis or benign prostatic hyperplasia (BPH).
Unfortunately, the biopsy procedure is invasive and can lead to complications. Common complications of a prostate biopsy may include bleeding, infection, sepsis / bacteremia, retention / urinary symptoms, and sexual dysfunction.
