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This test is recommended to evaluate and classify considered indeterminate thyroid nodules, including follicular lesion of undetermined significance (Follicular Lesion Undetermined Significance, FLUS)
When the doctor determines the presence of a thyroid nodule, the procedure is to perform a biopsy or fine needle aspiration (AAF). This process is performed to obtain Cellular tissue that will then be sent to the laboratory for the cytological study.
When the nodule is diagnosed as Intermediate (Bethesda III or IV Classification) surgery is usually performed to conclude whether the nodule is malignant or benign. In 70% of cases the result after surgery is benign. AFFIRMA GSC allows to reclassify undetermined nodules into benign or suspect, thus avoiding 50% of these diagnostic surgeries. With a negative predictive value of over 96%.